CV

Education

B.S. in GitHub, GitHub University, 2012
M.S. in Jekyll, GitHub University, 2014
Ph.D in Version Control Theory, GitHub University, 2018 (expected)

Work experience

Summer 2015: Research Assistant
- Github University
- Duties included: Tagging issues
- Supervisor: Professor Git
Fall 2015: Research Assistant
- Github University
- Duties included: Merging pull requests
- Supervisor: Professor Hub

Skills

Skill 1
Skill 2
- Sub-skill 2.1
- Sub-skill 2.2
- Sub-skill 2.3
Skill 3

Publications

Improved 2,4-diarylthiazole-based antiprion agents: switching the sense of the amide group at C5 leads to an increase in potency.

Nathan Adams, Thompson MJ, Louth JC, Greenwood GK, Sorrell FJ, Knight SG, Adams NB, Chen B, "Improved 2,4-diarylthiazole-based antiprion agents: switching the sense of the amide group at C5 leads to an increase in potency.." ChemMedChem, 2010.

Nonequilibrium isotope exchange reveals a catalytically significant enzyme-phosphate complex in the ATP hydrolysis pathway of the AAA(+) ATPase magnesium chelatase.

Nathan Adams, Adams NB, Reid JD, "Nonequilibrium isotope exchange reveals a catalytically significant enzyme-phosphate complex in the ATP hydrolysis pathway of the AAA(+) ATPase magnesium chelatase.." Biochemistry, 2012.

Synthesis and evaluation of anticancer natural product analogues based on angelmarin: targeting the tolerance towards nutrient deprivation.

Nathan Adams, Magolan J, Adams NB, Onozuka H, Hungerford NL, Esumi H, Coster MJ, "Synthesis and evaluation of anticancer natural product analogues based on angelmarin: targeting the tolerance towards nutrient deprivation.." ChemMedChem, 2012.

The allosteric role of the AAA+ domain of ChlD protein from the magnesium chelatase of synechocystis species PCC 6803.

Nathan Adams, Adams NB, Reid JD, "The allosteric role of the AAA+ domain of ChlD protein from the magnesium chelatase of synechocystis species PCC 6803.." Biochemistry, 2013.

Characterization of the magnesium chelatase from Thermosynechococcus elongatus.

Nathan Adams, Adams NB, Marklew CJ, Brindley AA, Hunter CN, Reid JD, "Characterization of the magnesium chelatase from Thermosynechococcus elongatus.." Biochemical Journal, 2014.

Structural and functional consequences of removing the N-terminal domain from the magnesium chelatase ChlH subunit of Thermosynechococcus elongatus.

Nathan Adams, Adams NB, Marklew CJ, Qian P, Brindley AA, Davison PA, Bullough PA, Hunter CN, "Structural and functional consequences of removing the N-terminal domain from the magnesium chelatase ChlH subunit of Thermosynechococcus elongatus.." Biochemical Journal, 2014.

Five Glutamic Acid Residues in the C-Terminal Domain of the ChlD Subunit Play a Major Role in Conferring Mg(2+) Cooperativity upon Magnesium Chelatase.

Nathan Adams, Brindley AA, Adams NB, Hunter CN, Reid JD, "Five Glutamic Acid Residues in the C-Terminal Domain of the ChlD Subunit Play a Major Role in Conferring Mg(2+) Cooperativity upon Magnesium Chelatase.." Biochemistry, 2015.

Porphyrin Binding to Gun4 Protein, Facilitated by a Flexible Loop, Controls Metabolite Flow through the Chlorophyll Biosynthetic Pathway.

Nathan Adams, Kope\v{c}n{\'a} J, Cabeza Vaca, Adams NB, Davison PA, Brindley AA, Hunter CN, Guallar V, Sobotka R, "Porphyrin Binding to Gun4 Protein, Facilitated by a Flexible Loop, Controls Metabolite Flow through the Chlorophyll Biosynthetic Pathway.." Journal of Biological Chemistry, 2015.

Nanomechanical and Thermophoretic Analyses of the Nucleotide-Dependent Interactions between the AAA⁺ Subunits of Magnesium Chelatase

N.B.P. Adams, C. Vasilev, A.A. Brindley, C.N. Hunter, "Nanomechanical and Thermophoretic Analyses of the Nucleotide-Dependent Interactions between the AAA⁺ Subunits of Magnesium Chelatase." Journal of the American Chemical Society, 2016.

Nanomechanical and thermophoretic analyses of the nucleotide-dependent interactions between the AAA(+) subunits of magnesium chelatase.

Nathan Adams, Adams NB, Vasilev C, Brindley AA, Hunter CN, "Nanomechanical and thermophoretic analyses of the nucleotide-dependent interactions between the AAA(+) subunits of magnesium chelatase.." JACS, 2016.

The catalytic power of magnesium chelatase: a benchmark for the AAA$mathplus$ATPases

Nathan Adams, Amanda Brindley, C. Hunter, James Reid, "The catalytic power of magnesium chelatase: a benchmark for the AAA$mathplus$ATPases." FEBS Lett, 2016.

The molecular basis of phosphite and hypophosphite recognition by ABC-transporters

Nathan Adams, Claudine Bisson, Nathan Adams, Ben Stevenson, Amanda Brindley, Despo Polyviou, Thomas Bibby, Patrick Baker, C. Hunter, Andrew Hitchcock, "The molecular basis of phosphite and hypophosphite recognition by ABC-transporters." Nature Communications, 2017.

Probing the quality control mechanism of the Escherichia coli twin-arginine translocase with folding variants of a de novo -designed heme protein

George Sutherland, Katie Grayson, Nathan Adams, Daphne Mermans, Alexander Jones, Angus Robertson, Dirk Auman, Amanda Brindley, Fabio Sterpone, Pierre Tuffery, Philippe Derreumaux, P. Dutton, Colin Robinson, Andrew Hitchcock, C. Hunter, "Probing the quality control mechanism of the Escherichia coli twin-arginine translocase with folding variants of a de novo -designed heme protein." Journal of Biological Chemistry, 2018.

The ChlD subunit links the motor and porphyrin binding subunits of magnesium chelatase

Nathan Adams, "The ChlD subunit links the motor and porphyrin binding subunits of magnesium chelatase." Biochemical Journal, 2019.

Phosphite binding by the HtxB periplasmic binding protein depends on the protonation state of the ligand

Nathan Adams, Angus Robertson, C. Hunter, Andrew Hitchcock, Claudine Bisson, "Phosphite binding by the HtxB periplasmic binding protein depends on the protonation state of the ligand." Scientific Reports, 2019.

The active site of magnesium chelatase

Nathan Adams, Claudine Bisson, Amanda Brindley, David Farmer, Paul Davison, James Reid, C. Hunter, "The active site of magnesium chelatase." Nature Plants, 2020.

How the O2-dependent Mg-protoporphyrin monomethyl ester cyclase forms the fifth ring of chlorophylls

Guangyu Chen, Nathan Adams, Philip Jackson, Mark Dickman, C Hunter, "How the O2-dependent Mg-protoporphyrin monomethyl ester cyclase forms the fifth ring of chlorophylls." Nature Plants, 2021.

Transporter characterisation reveals aminoethylphosphonate mineralisation as a key step in the marine phosphorus redox cycle

Andrew Murphy, David Scanlan, Yin Chen, Nathan Adams, William Cadman, Andrew Bottrill, Gary Bending, John Hammond, Andrew Hitchcock, Elizabeth Wellington, Ian Lidbury, "Transporter characterisation reveals aminoethylphosphonate mineralisation as a key step in the marine phosphorus redox cycle." Nature Communications, 2021.

Dr Nate Adams

CV